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Publications

 

2014

 

  1. Kumar A, Braun EL, Kimball RT. Tracing signals of brain evolution in Eutherian mammals. (Manuscript drafted for submission to Molecular Biology and Evolution and doing some additional analysis)

  2. Kumar A, Braun EL, Kimball RT. ConCat: Ultrafast alignment concatenation and analysis package. (Drafted for submission to Bioinformatics)

  3. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2014). Use of long term Molecular Dynamics Simulation in predicting cancer associated SNPs. PloS Computational Biology. 10 (4), e1003318.

  4. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2014). Role of Centrosome in Regulating Immune Response. Curr Drug Targets. 15 (5), 558-563.

 

 

2013

  1. Balu K, Kumar A, Purohit R (2013). Evolutionary reconstruction and population genetics analysis of Aurora kinases. PLoS ONE 8(9): e75763. doi:10.1371/journal.pone.0075763.

  2. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2013). RAC1 F28L mutation affects the conformational stability of Switch I region. PloS One. 8(10): e77453. Doi: 10.1371/journal.pone.0077453.

  3. Kumar A, Purohit R (2013). Cancer Associated E17K mutation causes rapid conformational drift in AKT1 pleckstrin homology (PH) domain. PLoS ONE, 10.1371/journal.pone.0064364.

  4. Kumar A, Rajendran V, Sethumadhavan R, Shukla P, Tiwari S, Purohit R (2013). Computational SNP Analysis: Current Approaches and Future Prospects. Cell Biochem Biophys, 68:233-9.

  5. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2013). CEP proteins: The knights of centrosome dynasty. Protoplasma, 10.1007/s00709-013-0488-9.

  6. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2013). Computational investigation of cancer- associated molecular mechanism in aurora A (S155R) mutation. Cell. Biochem. Biophys. 2013 66(3):787-96.

  7. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2013). Evidence of colorectal cancer- associated mutation in MCAK: A computational report. Cell Biochem. Biophys., 67(3):837-51

  8. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2013). Relationship between a point mutation S97C in CK1δ protein and its affect on ATP-binding affinity. J. Biomol. Struct. Dyn. 32(3):394-405

  9. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2013). Roadmap to determine the point mutations involved in cardiomyopathy disorder: A Bayesian approach. Gene, 519: 34-40.

  10. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2013). AKT kinase pathway: A leading target in cancer research. ScientificWorldJournal. 2013: 756134.

  11. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2012). Identifying novel oncogenes: a machine learning approach. Interdiscip. Sci. 5(4): 241-6.

 

 

2012

  1. Kumar A, Purohit R (2012). Computational screening and molecular dynamics simulation of disease associated nsSNPs in CENP-E. Mutat. Res., 738-739: 28-37.

  2. Kumar A, Purohit R (2012). Computational Centrosomics: An Approach to Understand the Dynamic Behaviour of Centrosome. Gene, 511: 125-126.

  3. Gulati G, Gaonkar KS, Kamraj B, Kumar A, Purohit R (2012). Structure based energy calculation to determine the regulation of G protein signalling by RGS and RGS-G protein interaction specificity. Interdiscip. Sci., 4: 173-182.

  4. Kumar A, Purohit R (2012). Computational Investigation of Pathogenic nsSNPs in CEP63 Protein. Gene, 503: 75-82.

  5. Kumar A, Rajendran V, Sethumadhavan R, Purohit R (2012). Insight into Nek2A activity regulation and its pharmacological prospects. Egyp. J. Med. Hum. Genet. 14: 213-219.

  6. Pandey A, Kumar A, Purohit R (2012). Sequencing Closterium moniliferum: Future prospects in nuclear waste disposal. Egyp. J. Med. Hum. Genet, 14: 113-115.

 

 

Book Chapter

  • Application of Bioinformatics in Screening and Analysis of Pathological Mutations (In Press) (Biotechnology Vol. 6: Bioinformatics and Computational Biology)

 

   

Poster Presentations

  1. Joni E. Wright, Ambuj Kumar, J. Gordon Burleigh, Edward L. Braun, and Rebecca T. Kimball (2015). Unexpected Olfactory Receptor (OR) Gene Numbers Revealed In Two Cathartid Species That Demonstrate Discrete Sensory System Reliance During Foraging. SICB Annual Meeting 2015.

  2. Kumar A, Edward L. Braun and Rebecca T. Kimball (2014). Adaptive evolution of Cep63-CEP152 centrosome microcephaly ring in association with brain size shift in mammals. ISCB Student Council Symposium 2014.

  3. Kumar A (2014). Molecular dynamics analysis of chronic myeloid leukemia gatekeeper mutation. ISMB 2014.

  4. Braun EL, Kimball ET, Meiklejohn KA, Hosner PA, Kumar A, Glenn TC, Faircloth BC (2014). Small genomes in the era of big data: phylogeny and patterns of molecular evolution for mitogenomes in galliformes. AOU/COS/SCO 2014 C19

  5. Kumar A (2012). Computational Prioritization of NsSNP's Involved in causing breast cancer in human. Eur. J. Cancer, 48: S119-S119.

  6. Mishra M, Kumar A (2011). Computational analysis of genetic network involved in pancreatic cancer in human. ISCB Student Council Symposium 2011. BMC Bioinformatics, 10.1186/1471-2105-12-S11-A11.

  7. Kumar A, Mishra M, Bhardwaj D, Agarwal K (2011). In silico analysis and prevention of coxsackie virus b4 induced insulin dependent diabetes mellitus. ISMB 2011. F1000Posters 2011, 2: 1325

Ambuj Kumar

PhD Student, Bioinformatics 
Iowa State University
Editorial Board Member

International Journal of Pharmacy and Pharmaceutical Sciences

Trends Journal of Sciences Research

Journal Refree

International Journal of Computing and Digital Systems

The future belongs to those who believe in the beauty of their dreams

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